Mefloquine should be taken with food and plenty of water to minimize stomach upset. For malaria prevention, it's typically taken once weekly, starting 1-2 weeks before travel and continuing for 4 weeks after leaving the risk area. For treatment, follow your healthcare provider's specific dosage instructions.

Common side effects may include nausea, vomiting, diarrhea, stomach pain, dizziness, headache, and sleep disturbances. More serious side effects can include anxiety, depression, hallucinations, or other neuropsychiatric symptoms. Contact your doctor immediately if you experience severe side effects.

The use of Mefloquine during pregnancy should be carefully considered with your healthcare provider. While it may be used when the benefits outweigh the risks, alternative antimalarial medications may be preferred during pregnancy, especially in the first trimester.

Store Mefloquine at room temperature, away from moisture, heat, and light. Keep the medication in its original container with the lid tightly closed. Keep out of reach of children and pets. Do not use Mefloquine after the expiration date printed on the label.