Recommended Dosage Guidelines

Important dosing information for Mefloquin® Tablets USP 250mg for malaria treatment and prevention.

Important Notice

This medication should only be taken under medical supervision. Always consult with a healthcare professional before starting treatment.

Treatment of Uncomplicated Malaria

Patient Group Dosage Regimen Total Dose
Adults 5 tablets (1250mg) as a single dose 1250mg
Children (6 months - 16 years) 25mg/kg body weight as a single dose (max 1250mg) Based on weight

Important Notes for Treatment:

  • Take with food and at least 240ml (8oz) of water
  • Do not crush or chew tablets
  • If vomiting occurs within 1 hour, repeat the full dose
  • If vomiting occurs between 1-2 hours, give half dose

Malaria Prophylaxis (Prevention)

Patient Group Dosage Regimen Frequency
Adults 1 tablet (250mg) Once weekly
Children (6 months - 16 years) 5mg/kg body weight (max 250mg) Once weekly

Prophylaxis Schedule:

  • Start: 1 week before entering malaria-endemic area
  • During: Continue weekly throughout stay
  • After: Continue for 4 weeks after leaving endemic area

Missed Dose Instructions

For Prophylaxis:

  • If you miss a weekly dose, take it as soon as possible
  • Do not take double doses to make up for missed doses
  • Resume weekly schedule as soon as possible
  • If more than 7 days have passed, consult healthcare provider

For Treatment:

  • Treatment is typically a single dose
  • If vomiting occurs, follow the guidelines above
  • Consult healthcare provider immediately

Overdose Information

Emergency Information

In case of overdose, seek immediate medical attention or contact poison control center.

Symptoms of Overdose:

  • Severe nausea and vomiting
  • Dizziness and headache
  • Visual disturbances
  • Psychiatric symptoms (anxiety, confusion)
  • Cardiac arrhythmias
  • Seizures (in severe cases)

Administration Guidelines

With Food

Always take with food to reduce gastrointestinal side effects

With Water

Take with at least 240ml (8oz) of water

Timing

Take at the same time each week for prophylaxis

Whole Tablets

Swallow tablets whole, do not crush or chew

Duration of Therapy

Treatment Duration

Single dose therapy for acute malaria treatment

Prophylaxis Duration

Minimum 2 weeks before travel, continue during stay, and 4 weeks after return

Maximum Duration

Not recommended for prophylaxis longer than 1 year without medical supervision